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Complete avoidance of allergenic pollen or mold means moving to a place where the offending substance does not grow and where it is not present in the air. But even this extreme solution may offer only temporary relief since a person who is sensitive to a specific pollen or mold may subsequently develop allergies to new allergens after repeated exposure. For example, people allergic to ragweed may leave their ragweed-ridden communities and relocate to areas where ragweed does not grow, only to develop allergies to other weeds or even to grasses or trees in their new surroundings. Because relocating is not a reliable solution, allergy specialists do not encourage this approach.

There are other ways to evade the offending pollen: remaining indoors in the morning, for example, when the outdoor pollen levels are highest. Sunny, windy days can be especially troublesome. If individuals with pollen allergy must work outdoors, they can wear face masks designed to filter pollen out of the air and keep it from reaching their nasal passages. As another approach, some people take their vacations at the height of the expected pollinating period and choose a location where such exposure would be minimal. The seashore, for example, may be an effective retreat for many with pollen allergies.